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Goat Anti-human IgM/FITC

分类 抗人

参数

货号:SLS-EKKR-5430/FITC

免疫原:Full length plasma protein

克隆号:Polyclonal

规格:2mg/ml

状态和缓冲液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

浓度:2mg/1ml

保存条件:Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles.

使用建议:Flow-Cyt=1:100-1000 IF=1:100-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

描述

IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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