SCC antibody

分类肿瘤标志物

参数

货号：SLS-113-02

别名：Serpin B3, also known as Squamous Cell Carcinoma Antigen-1 (SCCA1)

免疫原：Human SCC

克隆号：S431

亚型：IgG1,kappa

规格：1mg/支

浓度：2-3mg/ml

配对： This antibody can be used as the detection antibody in a sandwich EIA and pairs with SLS-113-01 as the capture antibody.

纯度：>95% pure(SDS-PAGE).

保存条件：Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles.

批号：随货见

状态和缓冲液：0.01M PBS, 0.9% NaCl, pH 7.4 （0.095% Proclin300)

使用建议：Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

用途：This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using.

Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.

描述

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