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产品描述 | CEA is restricted to the apical face of intestinal epithelial cells in the adult but is more diffuse during embryonic development and in tumors. This is consistent with a role in the development and maintenance of epithelial architecture. CEA is upregulated in a wide variety of human tumors and is a commonly used cancer marker. It promotes tumor cell migration, invasion, adhesion, and metastasis. It also contributes to tumor formation by maintaining cellular proliferation in the presence of differentiation stimuli, and by blocking apoptosis following loss of ECM anchorage (anoikis). |
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产品别名 | Carcinoembryonic antigen (CEA), also known as CEACAM-5 and CD66e |
免疫原 | Human CEA |
货号 | SLS-102-04 |
克隆类型 | E3-82 |
亚型 | IgG1 |
规格 | 1mg/支 |
浓度 | 2-3mg/ml |
配对 | This antibody can be used for conjugation when paired with monoclonal antibody SLS-102-01 |
纯度 | >95% pure(SDS-PAGE). |
批号 | 随货见 |
状态和缓冲液 | 0.01M PBS, 0.9% NaCl, pH 7.4 |
使用建议 | Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. |
应用 | This product is only for the in vitro study, not intended for diagnostic use, please according to the laboratory standard operating procedures using. |
存储 | Stored at 2-8°C short term, -20°C or colder long term. Avoid multiple freeze/thaw cycles. |